Searchable abstracts of presentations at key conferences in endocrinology

ea0099rc2.3 | Rapid Communications 2: Calcium and Bone | Part I | ECE2024

Metformin prevents glucocorticoid-induced bone resorption in healthy subjects

Pfammatter Stephanie , Lisa Zanetti , Thierry Susanne , Meier Christian , Seelig Eleonora

Background: Glucocorticoids are crucial for treating various medical conditions due to their beneficial immunosuppressive effects. However, glucocorticoids also carry a high risk for osteoporosis. Notably, within just a few months of glucocorticoid therapy, bone density can be significantly reduced, and up to 5% of patients undergoing such treatment may experience fractures. There is promising evidence from preclinical studies and observations in patients with type 2 diabetes ...